English: Canonical and non-canonical Wnt signaling pathways. FZD, Frizzled; LRP 5/6, low-density lipoprotein receptor-related protein; DVL, Disheveled; CK1, casein kinase 1α; GSK3β, glycogen synthase kinase 3β; β-cat, β-catenin; APC, adenomatous polyposis coli; TCF/LEF, T-cell factor/lymphoid-enhancing factor; Wnt/PCP, Wnt/Planar cell polarity; ROR2, receptor tyrosine kinase-like orphan receptor 2; JNK, c-Jun N-terminal kinase; DAAMI, Disheveled Associated Activator Of Morphogenesis 1; ROCK, Rho-associated kinase; AP-1, the activating protein-1; PLC, phospholipase C γ; DAG, diacylglycerol; PIP2, phosphatidylinositol 4,5-bisphosphate; IP3, inositol 1,4,5-triphosphate; PKC, protein kinase C; CAMKII, Ca2+-calmodulin dependent kinase II; NFAT, nuclear factor of activated T-cells.