English: A — Simple methods involving the minimal media and extracellular matrix generate self-organized whole brain organoids. B — A cocktail of patterning molecules generates brain region-specific structures such as midbrain and hippocampal organoids. C — Fusion of different organoids permits the study of interaction and migration between various cell types of different brain regions. D — Mixed lineage organoids such as neuromuscular organoids allow the investigation of the interorgan interactions. E — Synthetic materials enhance maturation of organoids. F — Microfluidics develops vasculature in organoids.