PRH2 (англ.Proline rich protein HaeIII subfamily 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 12-ї хромосоми.[2] Довжина поліпептидного ланцюга білка становить 166 амінокислот, а молекулярна маса — 17 016[3].
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14: 2121—2127. 2004. PMID15489334DOI:10.1101/gr.2596504
Kauffman D.L., Bennick A., Blum M., Keller P.J. (1991). Basic proline-rich proteins from human parotid saliva: relationships of the covalent structures of ten proteins from a single individual. Biochemistry. 30: 3351—3356. PMID1849422DOI:10.1021/bi00228a001
Helmerhorst E.J., Sun X., Salih E., Oppenheim F.G. (2008). Identification of Lys-Pro-Gln as a novel cleavage site specificity of saliva-associated proteases. J. Biol. Chem. 283: 19957—19966. PMID18463091DOI:10.1074/jbc.M708282200
Azen E.A. (1998). A frequent mutation in the acidic proline-rich protein gene, PRH2, causing a Q147K change closely adjacent to the bacterial binding domain of the cognate salivary PRP (Pr1') in Afro-Americans. Hum. Mutat. 12: 72—72. PMID10627138DOI:10.1002/(SICI)1098-1004(1998)12:1<72::AID-HUMU18>3.0.CO;2-W
Maeda N., Kim H.-S., Azen E.A., Smithies O. (1985). Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system. J. Biol. Chem. 260: 11123—11130. PMID2993301
Kim H.-S., Maeda N. (1986). Structures of two HaeIII-type genes in the human salivary proline-rich protein multigene family. J. Biol. Chem. 261: 6712—6718. PMID3009472
