Матеріал з Вікіпедії — вільної енциклопедії.
STARD9 (англ. StAR related lipid transfer domain containing 9 ) – білок, який кодується однойменним геном, розташованим у людей на 15-й хромосомі.[3] амінокислот , а молекулярна маса — 516 343[4]
Послідовність амінокислот
10 20 30 40 50 MANVQVAVRV RPLSKRETKE GGRIIVEVDG KVAKIRNLKV DNRPDGFGDS REKVMAFGFD YCYWSVNPED PQYASQDVVF QDLGMEVLSG VAKGYNICLF AYGQTGSGKT YTMLGTPASV GLTPRICEGL FVREKDCASL PSSCRIKVSF LEIYNERVRD LLKQSGQKKS YTLRVREHPE MGPYVQGLSQ HVVTNYKQVI QLLEEGIANR ITAATHVHEA SSRSHAIFTI HYTQAILENN LPSEMASKIN LVDLAGSERA DPSYCKDRIA EGANINKSLV TLGIVISTLA QNSQVFSSCQ SLNSSVSNGG DSGILSSPSG TSSGGAPSRR QSYIPYRDSV LTWLLKDSLG GNSKTIMVAT VSPAHTSYSE TMSTLRYASS AKNIINKPRV NEDANLKLIR ELREEIERLK ALLLSFELRN FSSLSDENLK ELVLQNELKI DQLTKDWTQK WNDWQALMEH YSVDINRRRA GVVIDSSLPH LMALEDDVLS TGVVLYHLKE GTTKIGRIDS DQEQDIVLQG QWIERDHCTI TSACGVVVLR PARGARCTVN GREVTASCRL TQGAVITLGK AQKFRFNHPA EAAVLRQRRQ VGEAAAGRGS LEWLDLDGDL AASRLGLSPL LWKERRALEE QCDEDHQTPR DGETSHRAQI QQQQSYVEDL RHQILAEEIR AAKELEFDQA WISQQIKENQ QCLLREETWL ASLQQQQQED QVAEKELEAS VALDAWLQTD PEIQPSPFVQ SQKRVVHLQL LRRHTLRAAE RNVRRKKVSF QLERIIKKQR LLEAQKRLEK LTTLCWLQDD STQEPPYQVL SPDATVPRPP CRSKLTSCSS LSPQRLCSKH MPQLHSIFLS WDPSTTLPPR PDPTHQTSEK TSSEEHLPQA ASYPARTGCL RKNGLHSSGH GQPCTARAAL ARKGASAPDA CLTMSPNSVG IQEMEMGVKQ PHQMVSQGLA SLRKSANKLK PRHEPKIFTS TTQTRGAKGL ADPSHTQAGW RKEGNLGTHK AAKGASCNSL YPHGPRQTAG HGKAVKTFWT EYKPPSPSRA SKRHQRVLAT RVRNITKKSS HLPLGSPLKR QQNTRDPDTM VPLTDFSPVM DHSREKDNDL SDTDSNYSLD SLSCVYAKAL IEPLKPEERK WDFPEPENSE SDDSQLSEDS LAEKRYQSPK NRLGGNRPTN NRGQPRTRTR ASVRGFTAAS DSDLLAQTHR SFSLDSLIDA EEELGEDQQE EPFPGSADEI PTETFWHLED SSLPVMDQEA ICRLGPINYR TAARLDAVLP MSSSFYLDPQ FQPHCELQPH CELQPHCELQ PHCEQAESQV EPSYSEQADS LQGMQLSRES PLMSMDSWFS CDSKINPSSP PGIVGSLCPS PDMQEFHSCK GERPGYWPNT EELKPSDAET VLPYSSKLHQ GSTELLCSAR DEHTASAADT SRLSLWGIQR LIQPGADGTF QGRCIPDMTQ QGSSEASHNS SVSNVLAASA TTLTHVGSTH ERDWSALQQK YLLELSCPVL EAIGAPKPAY PYLEEDSGSL AQASSKGGDT LLPVGPRVSS NLNLNNFPVH LSRIRRLRAE KEQDSLNAKL EGVSDFFSTS EKEASYDETY SADLESLSAS RSTNAQVFAT ENAIPDSMTE ACEVKQNNLE ECLQSCRKPG LMTSSDEDFF QKNACHSNVT TATKADHWSQ GWAPLRKNSA VQPGQLSPDS HYPLEEEKTD CQESSKEAVR RHINVSFALP SGPELYLHSA PWNPLSSSLQ PPLLETFYVT KSRDALTETA LEIPACREVR VPSPPPREAW GFGHNHQALQ GAYLKNNLPV LLQNQNSKIA SSQQVTAEIP VDLNTREVIR ESGKCPGNIT EESHDSVYSS VTQNRHFLPS TSTKVCEFEN QVVILNKKHS FPALEGGEVT AQSCCGASSD STESGKSLLF RESEAREEEE LDQNTVLRQT INVSLEKDMP GESAVSLKSR SVDRRVSSPV MVAQGGGPTP KWEGKNETGL LEKGLRPKDS SEEFKLPGTK PAYERFQLVA CPQERNPSEC KSQEMLNPNR EPSGKKQNKR VNNTDEMARL IRSVMQLENG ILEIESKQNK QVHASHTPGT DKELVFQDQK EQEKTDHAFR PDSSGNPLPS KDQPSSPRQT DDTVFRDSEA GAMEVNSIGN HPQVQKITPN PFRSREGVRE SEPVREHTHP AGSDRPARDI CDSLGKHTTC REFTNTSLHP QRMKALARAL PLQPRLERSS KNNGQFVKAS ASLKGQPWGL GSLEELETVK GFQESQVAEH VSSSNQEEPK AQGKVEEMPM QRGGSLQEEN KVTQKFPSLS QLCRDTFFRQ ETVSPLLSRT EFCTAPLHQD LSNTLPLNSP RWPRRCLHVP VALGISSLDC VLDLTMLKIH NSPLVTGVEH QDQSTETRSH SPEGNVRGRS SEAHTAWCGS VRSMAMGSHS QSGVPESIPL GTEDRISAST SPQDHGKDLR ITLLGFSTSE DFASEAEVAV QKEIRVSSLN KVSSQPEKRV SFSLEEDSDQ ASKPRQKAEK ETEDVGLTSG VSLAPVSLPR VPSPEPRLLE PSDHASMCLA ILEEIRQAKA QRKQLHDFVA RGTVLSYCET LLEPECSSRV AGRPQCKQID QSSSDQTRNE GEAPGFHVAS LSAEAGQIDL LPDERKVQAT SLSADSFESL PNTETDREPW DPVQAFSHAA PAQDRKRRTG ELRQFAGASE PFICHSSSSE IIEKKKDATR TPSSADPLAP DSPRSSAPVE EVRRVVSKKV VAALPSQAPY DDPRVTLHEL SQSVPQETAE GIPPGSQDSS PEHQEPRTLD TTYGEVSDNL LVTAQGEKTA HFESQSVTCD VQNSTSASGP KQDHVQCPEA STGFEEGRAS PKQDTILPGA LTRVALEAPT QQCVQCKESV GSGLTEVCRA GSKHSRPIPL PDQRPSANPG GIGEEAPCRH PREALDGPVF SRNPEGSRTL SPSRGKESRT LPCRQPCSSQ PVATHAYSSH SSTLLCFRDG DLGKEPFKAA PHTIHPPCVV PSRAYEMDET GEISRGPDVH LTHGLEPKDV NREFRLTESS TCEPSTVAAV LSRAQGCRSP SAPDVRTGSF SHSATDGSVG LIGVPEKKVA EKQASTELEA ASFPAGMYSE PLRQFRDSSV GDQNAQVCQT NPEPPATTQG PHTLDLSEGS AESKLVVEPQ HECLENTTRC FLEKPQFSTE LRDHNRLDSQ AKFVARLKHT CSPQEDSPWQ EEEQHRDQAS GGGEGFAQGV NPLPDEDGLD GCQILDAGRE EVAVAKPPVS KILSQGFKDP ATVSLRQNET PQPAAQRSGH LYTGREQPAP NHRGSLPVTT IFSGPKHSRS SPTPQFSVVG SSRSLQELNL SVEPPSPTDE DTQGPNRLWN PHLRGYSSGK SVARTSLQAE DSNQKASSRL DDGTTDHRHL KPATPPYPMP STLSHMPTPD FTTSWMSGTL EQAQQGKREK LGVQVRPENW CSQMDKGMLH FGSSDISPYA LPWRPEEPAR ISWKQYMSGS AVDVSCSQKP QGLTLSNVAR CSSMDNGLED QNSPFHSHLS TYANICDLST THSSTENAQG SNEAWEVFRG SSSIALGDPH IPTSPEGVAP TSGHDRRPQF RGPSGEADCL RSKPPLAKGS AAGPVDEIML LYPSEAGCPV GQTRTNTFEQ GTQTLGSRRH WSSTDISFAQ PEASAVSAFD LASWTSMHNL SLHLSQLLHS TSELLGSLSQ PDVARREQNT KRDIPDKAPQ ALMMDGSTQT TVDEGSQTDL TLPTLCLQTS EAEPQGANVI LEGLGSDTST VSQEEGDVPG VPQKREAEET AQKMAQLLYL QEESTPYKPQ SPSIPSSHLR FQKAPVGQHL PSVSPSVSDA FLPPSSQPEE SYCLVVSSPS PSSPHSPGLF PSTSEYPGDS RVQKKLGPTS ALFVDRASSP ILTLSASTQE PGLSPGSLTL SAPSTHPVEG HQKLDSSPDP VDAPRTPMDN YSQTTDELGG SQRGRSSLQR SNGRSFLELH SPHSPQQSPK LQFSFLGQHP QQLQPRTTIG VQSRLLPPPL RHRSQRLGNS FVPEKVASPE HCPLSGREPS QWQSRTENGG ESSASPGEPQ RTLDRPSSWG GLQHLSPCPV SELTDTAGLR GSALGLPQAC QPEELLCFSC QMCMAPEHQH HSLRDLPVHN KFSNWCGVQK GSPGGLDMTE EELGASGDLS SEKQEQSPPQ PPNDHSQDSE WSKREQIPLQ VGAQNLSLSV ELTEAKLHHG FGEADALLQV LQSGTGEALA ADEPVTSTWK ELYARQKKAI ETLRRERAER LGNFCRTRSL SPQKQLSLLP NKDLFIWDLD LPSRRREYLQ QLRKDVVETT RSPESVSRSA HTPSDIELML QDYQQAHEEA KVEIARARDQ LRERTEQEKL RIHQKIISQL LKEEDKLHTL ANSSSLCTSS NGSLSSGMTS GYNSSPALSG QLQFPENMGH TNLPDSRDVW IGDERGGHSA VRKNSAYSHR ASLGSCCCSP SSLSSLGTCF SSSYQDLAKH VVDTSMADVM AACSDNLHNL FSCQATAGWN YQGEEQAVQL YYKVFSPTRH GFLGAGVVSQ PLSRVWAAVS DPTVWPLYYK PIQTARLHQR VTNSISLVYL VCNTTLCALK QPRDFCCVCV EAKEGHLSVM AAQSVYDTSM PRPSRKMVRG EILPSAWILQ PITVEGKEVT RVIYLAQVEL GAPGFPPQLL SSFIKRQPLV IARLASFLGR
Кодований геном білок за функціями належить до білкових моторів , фосфопротеїнів .
Задіяний у такому біологічному процесі, як альтернативний сплайсинг .
Білок має сайт для зв'язування з АТФ , нуклеотидами .
Локалізований у цитоплазмі , цитоскелеті , ядрі .
Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. (2000). Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. DNA Res . 7 : 65—73. PMID 10718198 DOI :10.1093/dnares/7.1.65 Halama N., Grauling-Halama S.A., Jager D. (2006). Identification and characterization of the human StARD9 gene in the LGMD2A-region on chromosome 15q15 by in silico methods. Int. J. Mol. Med . 18 : 653—656. PMID 16964419
