XBP1 (англ.X-box binding protein 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 22-ї хромосоми.[4] Довжина поліпептидного ланцюга білка становить 261 амінокислот, а молекулярна маса — 28 695[5].
Yoshida H., Matsui T., Yamamoto A., Okada T., Mori K. (2001). XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.. Cell107: 881 — 891.PubMedDOI:10.1016/S0092-8674(01)00611-0
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res.14: 2121 — 2127. 2004.PubMedDOI:10.1101/gr.2596504
Ono S.J., Liou H.C., Davidon R., Strominger J.L., Glimcher L.H. (1991). Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.. Proc. Natl. Acad. Sci. U.S.A.88: 4309 — 4312.PubMedDOI:10.1073/pnas.88.10.4309
Clauss I.M., Chu M., Zhao J.-L., Glimcher L.H. (1996). The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core.. Nucleic Acids Res.24: 1855 — 1864.PubMedDOI:10.1093/nar/24.10.1855
Sriburi R., Jackowski S., Mori K., Brewer J.W. (2004). XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.. J. Cell Biol.167: 35 — 41.PubMedDOI:10.1083/jcb.200406136
Yoshida H., Nadanaka S., Sato R., Mori K. (2006). XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells.. Cell Struct. Funct.31: 117 — 125.PubMedDOI:10.1247/csf.06016